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AssigneeSumitomo Pharma America, Inc.
InventorsLinda Jane BRISTOW, Nina DEDIC, Eva HAJOS-KORCSOK, Seth Cabot HOPKINS, Philip Glyn JONES, Kenneth S. KOBLAN, Snezana MILANOVIC, Colleen Marie SYNAN, Kuangnan XIONG
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Provided herein are compounds, pharmaceutical compositions, and methods of use thereof, including methods of treating metabolic disorders and psychiatric disorders and diseases associated with metabolic disorders. For example, provided herein is Compound 1: or a pharmaceutically acceptable salt thereof, and pharmaceutical compositions and methods of use thereof, including methods of treating metabolic disorders and psychiatric disorders associated with metabolic disorders.
A method of treating schizophrenia, depression, or anxiety in a human subject in need thereof, comprising administering to the subject a therapeutically effective amount of Compound 1, or a pharmaceutically acceptable salt thereof, wherein the subject's body fat is reduced.
A method of treating schizophrenia, depression, or anxiety in a human subject in need thereof, comprising administering to the subject a therapeutically effective amount of Compound 1, or a pharmaceutically acceptable salt thereof, wherein the subject's weight is statistically significantly reduced.
A method of treating schizophrenia, depression, or anxiety in a human subject in need thereof, comprising administering to the subject a therapeutically effective amount of Compound 1, or a pharmaceutically acceptable salt thereof, wherein the subject has improved insulin sensitivity.
A method of reducing body fat in a human subject having schizophrenia, depression, or anxiety, comprising administering to the subject a therapeutically effective amount of Compound 1, or a pharmaceutically acceptable salt thereof.
A method of reducing the weight in a human subject having schizophrenia, depression, or anxiety, comprising administering to the subject a therapeutically effective amount of Compound 1, or a pharmaceutically acceptable salt thereof.
(canceled)
Dependencies are inferred from the claim text.