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US 2026/0215780 A1Published application
Nerve conduit system
AssigneeTissium
InventorsMarie Malafosse, Elise Devries, Estelle Collin
Life of this patent
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AssigneeTissium
InventorsMarie Malafosse, Elise Devries, Estelle Collin
Estimating the term…
A nerve conduit systems supporting a repair of nerve lesions by facilitating proper placement and orientation of the nerve ends and enabling the connection of nerve ends having same or different diameters. Accordingly, a nerve conduit system for connecting two nerve ends in an end-to-end manner includes a first part and a second part, each part including an insertion portion each being adapted to receive one of the two nerve ends, and a connection portion, each part includes a through-hole being defined at least by the respective insertion portion and extending between longitudinally opposing ends of the respective part and the connection portions are configured to engage each other and are arranged such that the through-holes are in fluid communication with each other in a connected state, i.e. when the connection portions of the first part and of the second part are engaged.
A nerve conduit system (10) for connecting two nerve ends in an end-to-end manner, comprising a first part (12) and a second part (14), each part (12, 14) comprising an insertion portion (16, 26) each being adapted to receive one of the two nerve ends, and a connection portion (22, 24),
The nerve conduit system (10) according to any one of the preceding claims, wherein the insertion portion (16, 26) and/or the connection portion (22, 24) of at least one part (12, 14), preferably of each part (12, 14), has an essentially cylindrical shape.
The nerve conduit system (10) according to any one of the preceding claims, wherein the connection portion (22, 24) of at least one part (12, 14), preferably of the second part (14), at least partially surrounds the insertion portion (16, 26) of said part (12, 14).
The nerve conduit system (10) according to any one of the preceding claims, wherein the insertion portion (16, 26) and the connection portion (22, 24) of at least one part (12, 14), preferably of the first part (12), are arranged adjacent to each other in longitudinal direction.
The nerve conduit system (10) according to any of the preceding claims, wherein the connection portions (22, 24) are configured such that the insertion portions (16, 26) are arranged at longitudinally opposing ends of the nerve conduit system (10) when the connection portions (22,24) of the first (12) and second part (14) are engaged.
The nerve conduit system (10) according to any of the preceding claims, wherein the through-holes (20, 30) of the first and second part (12, 14) define a single longitudinal axis of the nerve conduit system (10) when the connection portions (22,24) of the first (12) and second part (14) are engaged.
The nerve conduit system (10) according to any of the preceding claims, wherein the connection portions (22, 24) are configured such that the through-hole (30) of the second part (14) is at least partially accommodated within the through-hole (20) of the first part (12) when the connection portions (22,24) are engaged.
The nerve conduit system (10) according to any of the preceding claims, wherein a transition portion (18) of the first part (12) is configured to at least partially receive and accommodate a radially expanding end portion (29) of the insertion portion (26) of the second part (14) when the connection portions (22,24) of the first (12) and second part (14) are engaged.
The nerve conduit system (10) according to any of the preceding claims, wherein the insertion portion (26) and/or a radially expanding end portion (29) of the insertion portion (26) of the second part (14) extends beyond the respective connection portion (24) in the longitudinal direction.
The nerve conduit system (10) according to any of the preceding claims, wherein the connection portion (24) of the second part (14) extends from a longitudinal end portion of the respective insertion portion (26) being configured to receive and/or insert the respective nerve end or with a longitudinal offset to a longitudinal end portion of the respective insertion portion being configured to receive and/or insert the respective nerve end.
The nerve conduit system (10) according to any of the preceding claims, wherein the connection portion (22) of the first part (12) is arranged adjacent to a respective transition portion (18) or a longitudinal end portion of the respective insertion portion (16) opposing a longitudinal end portion of the respective insertion portion (16) being configured to receive and/or insert the respective nerve end.
The nerve conduit system (10) according to any of the preceding claims, wherein at least a portion of the through-hole (20, 30), which is defined by the insertion portion (16, 26) of the first and/or second part (12, 14), is defined by a tubular shaped wall defining an essentially constant inner diameter.
The nerve conduit system (10) according to any of the preceding claims, wherein the connection portion (22) of the first part (12) is formed by a single circumferential wall (23) and wherein the single wall (23) accommodates the connection portion (24) of the second part (14) at the inner surface or outer surface of said wall (23).
The nerve conduit system (10) according to any of the preceding claims, wherein each connection portion (22, 24) comprises at least one circumferential wall (23) and the circumferential walls (23) are configured to engage and radially bias each other and/or are dimensioned and configured to engage each other by interference fit when the connection portions (22,24) of the first (12) and second part (14) are engaged.
The nerve conduit system (10) according to any of the preceding claims, wherein one of the connection portions (22, 24) comprises at least one radially extending protrusion (36) and the other connection portion (22, 24) comprises at least one slit or groove (38) configured to receive said protrusion (36) and, preferably, to at least longitudinally secure the second part (14) to the first part (12) when the connection portions (22,24) of the first (12) and second part (14) are engaged.
The nerve conduit system (10) according to any of the preceding claims, wherein the cross-sectional area of the through-hole (20, 30) of the insertion portion (16, 26) of the first part (12) and/or the second part (14) is gradually increased at a longitudinal end portion for receiving the nerve end and in a direction facing away from the respective connection portion (22, 24).
The nerve conduit system (10) according to any of the preceding claims, wherein a transition portion (18, 28) of the first part (12) and/or the second part (14) is configured to steplessly connect the respective insertion portion (16, 26) having a first diameter with the respective connection portion (22, 24) having a second diameter different from the first diameter.
The nerve conduit system (10) according to any of the preceding claims, wherein the connection portion (22) of the first part (12) defines a stop (32), said stop (32) being configured to abut the connection portion (24) of the second part (14) when the connection portions (22,24) of the first (12) and second part (14) are engaged.
The nerve conduit system (10) according to any of the preceding claims, wherein at least one part (12, 14) comprises one or more gripping ribs (34), which protrude radially outward of the outer surface of a wall of said connection portion (22, 24) and which preferably longitudinally extend at or along the outer surface of said part (12, 14).
The nerve conduit system (10) according to any of the preceding claims, wherein a wall (23) of the connection portion (22) of the first part (12) comprises a transparent window or opening arranged at a predefined longitudinal offset to a free end of the connection portion (22) of the first part (12).
A kit of parts, comprising a nerve conduit system (10) according to any of the preceding claims, wherein the kit comprises two or more first parts (12) being adapted for different nerve end diameters and/or two or more second parts (14) being adapted for different nerve end diameters, wherein the connection portions (22, 24) of said parts are adapted such that each first part (12) of the kit is connectable to each second part (14) of the kit.
Dependencies are inferred from the claim text.