US 2026/0207068 A1 · METHOD FOR MONITORING BLOOD PRESSURE

Abstract

Methods and systems are provided herein for measuring a blood pressure (BP) of a subject when continuous monitoring is desired, and a traditional cuff-based blood pressure measurement system may be restrictive. The proposed systems and methods measure the BP using dual photoplethysmography (PPG) sensors integrated into the cuff, which can dramatically reduce the frequency of cuff inflation while providing continuous BP monitoring. The dual PPG sensors monitor a BP of a patient by calculating a Pulse Wave Velocity (PWV) of blood in a blood vessel of the patient based on a Pulse Transit Time (PTT), and an PPG Intensity Ratio (PIR). The patient's BP may be measured continuously based on these physiological parameters, with the cuff serving as a reference to periodically recalibrate the system automatically, thereby enhancing accuracy and reducing a demand for frequent cuff inflation.

Claims20

Dependent claims

A system for monitoring a blood pressure (BP) of a patient, comprising:

a BP measurement device including a cuff;
at least two photoplethysmography (PPG) sensors arranged in the cuff such that when the cuff is fastened around an arm of the patient, the at least two PPG sensors are positioned to sense a flow of blood in a brachial artery of the patient;
and
a controller and a memory storing instructions that when executed, cause the controller to:
receive PPG signals from the at least two PPG sensors;
calculate an instantaneous blood pressure (BP) of the patient based on the received PPG signals;
display an arterial BP waveform generated from a plurality of instantaneous BP measurements on a display device;
and
periodically recalibrate the arterial BP waveform based on a reference signal measured by the at least two PPG sensors.

6 more elements

A method for continuous monitoring of a blood pressure (BP) of a patient, the method comprising:

at regular time intervals during the continuous monitoring:
receiving a first photoplethysmography (PPG) signal from a first PPG sensor positioned on an arm of the patient;
receiving a second PPG signal from a second PPG sensor positioned on the arm;
receiving diastolic PPG measurements acquired from both of the first PPG sensor and the second PPG sensor during a diastole of a cardiac cycle of the patient;
calculating a Pulse Transit Time (PTT) of the patient based on the first PPG signal and the second PPG signal;
calculating a Pulse Wave Velocity (PWV) of the patient based on the PTT;
calculating an average PPG Intensity Ratio (PIR) of the cardiac cycle of a first PIR based on the first PPG signal and a second PIR based on the second PPG signal;
calculating an instantaneous pulse pressure (PP) of the patient based on the PWV and the PIR;
converting the instantaneous PP into an instantaneous BP measurement;
displaying on a display device, in real time, an arterial BP waveform generated from a plurality of instantaneous BP measurements generated at the regular time intervals;
and
recalibrating the arterial BP waveform in response to either of the diastolic PPG measurements deviating from a reference diastolic PPG measurement measured by the first PPG sensor and/or the second PPG sensor by a threshold amount.

9 more elements

A method for generating an arterial blood pressure (BP) waveform of a patient, the method comprising:

receiving instantaneous photoplethysmography (PPG) measurements generated at regular time intervals from the patient via a plurality of PPG sensors positioned on a brachial artery of the patient;
generating a Pulse Pressure (PP) waveform from the instantaneous PPG measurements based on a Pulse Transit Time (PTT) of the patient measured between locations of the plurality of PPG sensors, and PPG Intensity Ratio (PIR) of the patient measured from the plurality of PPG sensors;
and
adjusting the instantaneous PP measurements by applying a general calibration function based on reference BP measurements collected in advance from a plurality of subjects.

1 more element

Dependencies are inferred from the claim text.

Method for monitoring blood pressure

Life of this patent

Method for monitoring blood pressure

Life of this patent

Abstract

Claims20