Carbon dioxide well injection simulation techniques

A method of simulating carbon dioxide injection into a saline aquifer, the method comprising:

• obtaining geological reference data correlated to a saline aquifer formation layer;
• establishing a set of carbon dioxide injection parameters for simulation of an application to at least one injection well in communication with the saline aquifer;
• mathematically partitioning the saline aquifer formation layer into a plurality of discrete partitions based on the geological reference data;
• plotting pseudo-node points of interest within one or more of the discrete partitions;
• and
• estimating carbon dioxide flow characteristics for each discrete partition of the plurality based on the geological reference data and the carbon dioxide injection parameters, wherein the estimating includes ascertaining flow characteristics at the pseudo-node point of interest at a given point in time related to the carbon dioxide injection parameters.