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US 2026/0193226 A1Published application
Microbiocidal tetrahydroisoquinoline derivatives
AssigneeSyngenta Crop Protection AG
InventorsAndrew EDMUNDS, Christopher Charles SCARBOROUGH, Atul MAHAJAN, Federico DAPIAGGI, Stefano RENDINE, Daniel EMERY, Myriem EL QACEMI
Life of this patent
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Abstract
A compound of formula (I) wherein the substituents are as defined in claim 1, and the agrochemically acceptable salts, stereoisomers, enantiomers, tautomers and N-oxides of those compounds, which can be used as fungicides.
Claims15
A compound of formula (I)
- wherein
- R1 is selected from hydrogen, C1-C4-alkyl, C2-C4-alkenyl, C2-C4-alkynyl, or C3-C6-cycloalkyl;
- R2 is selected from hydrogen, halogen, C1-C4-alkyl, C2-C4-alkenyl, C2-C4-alkynyl, C1-C4-haloalkyl, C3-C6-cycloalkyl, C1-C4-alkylcarbonyl, N—C1-C4-alkoxy-C—C1-C4-alkyl-carbonimidoyl, N-hydroxy-C—C1-C4 alkyl-carbonimidoyl, or C1-C4-alkoxycarbonyl;
- R3 is selected from hydrogen, halogen, C1-C4-haloalkyl, or C1-C4-alkyl;
- R4 is selected from hydrogen, halogen, C1-C4-haloalkyl, C3-C6-cycloalkyl, or C1-C4-alkyl;
- R5 and R6 are independently selected from hydrogen, or C1-C4-alkyl;
- R7 is selected from hydrogen, C1-C4-alkyl, C1-C4-alkylcarbonyl, N—C1-C4-alkoxy-C—C1-C4-alkyl-carbonimidoyl, N-hydroxy-C—C1-C4-alkyl-carbonimidoyl, C1-C4-alkoxycarbonyl, N-methoxy-N-methyl-carbonyl, C1-C4-alkylaminocarbonyl, di(C1-C4-alkylamino)carbonyl, phenyl, a 5- to 6-membered heteroaryl, or C3-C6-cycloalkyl;
- wherein said 5- to 6-membered heteroaryl contains 1, 2, 3 or 4 identical or different heteroatoms selected from N, O, or S, with the proviso that no more than one is O or S;
- wherein said phenyl and 5- to 6-membered heteroaryl are unsubstituted or substituted with 1, 2 or 3 identical or different substituents selected from the group consisting of halogen, C1-C4-haloalkyl, cyano, carboxy, C1-C4-alkyl and C1-C4-alkoxy;
- and wherein said C3-C6-cycloalkyl is unsubstituted or substituted with 1, 2 or 3 identical or different substituents selected from the group consisting of halogen, C1-C4-haloalkyl, cyano, C1-C4-alkyl, or C1-C4-alkoxy;
- B1 is selected from CR10, or N;
- B2 is selected from CR11, or N;
- R1, R9, R10 and R11 are independently selected from hydrogen, halogen, C1-C4-alkyl, C1-C4-haloalkyl, C1-C4-alkoxy, C1-C4-haloalkoxy, C2-C4-alkenyloxy, C2-C4-alkynyloxy, C1-C4-alkylsulfanyl, C1-C4 alkylsulfinyl, C1-C4-alkylsulfonyl, C1-C4-alkoxy-C1-C4-alkyl, N—C1-C4-alkylamino, N,N-di(C1-C4-alkyl)amino, C1-C4-alkoxycarbonyl, C1-C4-alkylcarbonyl, N—C1-C4-alkoxy-C1-C4-alkyl-carbonimidoyl, N-hydroxy-C1-C4 alkyl-carbonimidoyl, hydroxy, trifluoromethylsulfonyloxy, cyano, carboxy, amino, phenyl, 5- to 6-membered heteroaryl, or C3-C6 cycloalkyl;
- wherein said 5- to 6-membered heteroaryl contains 1, 2, 3 or 4 identical or different heteroatoms selected from N, O, or S, with the proviso that no more than one is O or S;
- and wherein any of said phenyl, 5- to 6-membered heteroaryl and C3-C6-cycloalkyl are unsubstituted or substituted with 1, 2, 3 or up to the maximum possible number of identical or different substituents selected from the group consisting of halogen, cyano, C1-C4-alkyl, C1-C4-haloalkyl, and C1-C4-alkoxy;
- W is selected from O, N, S, *—CH2O—#, “—CH2NH—#, “—CH2S—#, or a bond, wherein the star (*) denotes the position which is attached to the carbonyl-group, and #denotes the position, which is attached to Z1;
- and
- Z1 is selected from C1-C6 alkyl, phenyl, or a 6-membered heteroaryl;
- wherein said C1-C6-alkyl is unsubstituted or substituted with 1, 2 or 3 identical or different substituents selected from halogen, C1-C4-alkyl, C2-C4-alkenyl, C2-C4-alkynyl, C1-C4-haloalkyl, C1-C4-alkoxy, C1-C4-haloalkoxy, C2-C4-alkenyloxy, C2-C4-alkynyloxy, C1-C4-alkylsulfanyl, C1-C4-alkylsulfinyl, C1-C4-alkylsulfonyl, C1-C4-alkoxy-C1-C4-alkyl, C1-C4-alkoxycarbonyl, C1-C4-alkylcarbonyl, N—C1-C4-alkoxy-C—C1-C4-alkyl-carbonimidoyl, N-hydroxy-C—C1-C4-alkyl-carbonimidoyl, hydroxy, trifluoromethylsulfonyloxy, cyano, carboxy, phenyl, a 5- to 6-membered saturated or partially saturated heterocycle, 5- to 6-membered heteroaryl, or C3-C6-cycloalkyl;
- wherein any of said 6-membered heteroaryl and said 5- to 6-membered heteroaryl contains 1, 2 or 3 identical or different heteroatoms selected from N, O, or S, with the proviso that no more than one is O or S;
- wherein any of said 5- to 6-membered saturated or partially saturated heterocycle contains 1, 2, or 3 identical or different heteroatoms selected from N, O, or S, with the proviso that no more than one is O or S;
- wherein any of said phenyl, any of said 6-membered heteroaryl, any of said 5- to 6-membered heteroaryl and any of said 5- to 6-membered saturated or partially saturated heterocycle, are unsubstituted or substituted with 1, 2, 3 or up to the maximum possible number of identical or different substituents selected from the group consisting of halogen, cyano, C1-C4-alkyl, C1-C4-haloalkyl, C3-C6-cycloalkyl, and C1-C4-alkoxy;
- and wherein any of said C3-C6-cycloalkyl is unsubstituted or substituted with 1, 2, 3 or up to the maximum possible number of identical or different substituents selected from the group consisting of halogen, cyano, C1-C4-alkyl, C1-C4-haloalkyl, and C1-C4-alkoxy;
- or an agrochemically acceptable salt, stereoisomer, or N-oxide thereof, with the proviso that the compound of formula (I) is not
- or an agrochemically acceptable salt, stereoisomer, enantiomer, tautomer or N-oxide thereof.
22 more elements
Dependencies are inferred from the claim text.