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US 2026/0192020 A1Published application
Nerve grafts containing regenerative compounds, methods of making the same, and methods of treatment using the same
AssigneeAxogen Corporation
InventorsKasra TAJDARAN, Angelo SCOPELIANOS
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Abstract
A method of preparing a nerve graft includes submerging a nerve graft in a solution including FK506 and a solvent to promote incorporation of FK506 into the nerve graft. A tissue graft includes nerve tissue and FK506 incorporated within the nerve tissue. In the tissue graft, the FK506 is free of hydrogel and not encapsulated.
Claims20
A method of preparing a nerve graft, the method comprising:
- submerging a nerve graft in a solution comprising FK506 and a solvent to promote incorporation of FK506 into the nerve graft.
A method of preparing a nerve graft, the method comprising:
- exposing a nerve graft to a solution comprising FK506 such that the FK506 is at least partially incorporated within one or more portions of the nerve graft;
- sterilizing the nerve graft;
- and
- storing the nerve graft.
1 more element
A tissue graft, comprising:
- nerve tissue;
- and
- FK506 incorporated within the nerve tissue, the FK506 being free of hydrogel and not encapsulated.
Dependencies are inferred from the claim text.