Delivery of bacteria-derived outer membrane vesicles
AssigneeQuadram Institute Bioscience
InventorsSimon Carding, Regis Stentz
Life of this patent
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Abstract
Pharmaceutical compositions and preparation including outer membrane vesicles (OMVs) and at least one pharmaceutically acceptable carrier wherein said OMVs are native OMVs produced by the Gram-negative commensal bacteria Bacteroides.
Claims21
1-35. (canceled)
A method of treating a gastrointestinal (GI) tract auto-immune disease, crohn's disease or colitis, the method comprising administering to a subject in need thereof a pharmaceutical preparation including a therapeutically effective amount of outer membrane vesicles (OMVs) and at least one pharmaceutically acceptable carrier, wherein said OMVs are native OMVs by the Gram-negative commensal bacteria Bacteroides.
A method of treating tumour growth or cancer, the method comprising administering to a subject in need thereof a pharmaceutical preparation including a therapeutically effective amount of outer membrane vesicles (OMVs) and at least one pharmaceutically acceptable carrier, wherein said OMVs are native OMVs by the Gram-negative commensal bacteria Bacteroides.
A method of treating typhoid, the method comprising administering to a subject in need thereof a pharmaceutical preparation including a therapeutically effective amount of outer membrane vesicles (OMVs) and at least one pharmaceutically acceptable carrier, wherein said OMVs are native OMVs by the Gram-negative commensal bacteria Bacteroides.
Dependencies are inferred from the claim text.