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US 2026/0176295 A1Published application
Phosphonate conjugates and uses thereof
AssigneesThe Translational Genomics Research Institute, University of Utah Research Foundation
InventorsHariprasad Vankayalapati, Sunil Sharma, Alana L. Welm
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Abstract
Phosphonate conjugates, preferably, bisphosphonate conjugates; methods of inhibiting Ron receptor tyrosine kinase and methods of treatment of bone destruction due to cancer or other conditions utilizing the provided phosphonate conjugates.
Claims14
A phosphonate conjugate with compound A, wherein compound A has the following structural formula:
- and wherein the phosphonate is directly conjugated to compound A, or a pharmaceutically acceptable salt, isomer, hydrate, solvate, or polymorph of the conjugate.
Dependencies are inferred from the claim text.