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US 2026/0166295 A1Published application
Systems and Methods for Ablating a Tissue Region
AssigneeUniversity of Iowa Research Foundation
InventorSteven Richard Mickelsen
Life of this patent
Estimating the term…
Abstract
Systems and methods for ablating a target tissue of a heart. The systems and methods are configured to selectively activate subsets electrodes of an ablation system to produce pulsed waveforms forming different vectors directed towards the target tissue to cause irreversible electroporation of the target tissue.
Claims26
A method for ablating a target tissue of a heart, comprising:
- selectively activating a first subset of at least three electrodes of an ablation system to produce a first pulsed waveform, wherein the first pulsed waveform produces a first electric field having a first vector with a first controlled direction toward the target tissue;
- and
- selectively activating a second subset of the at least three electrodes after selective activation of the first subset, the second subset different than the first subset, to produce a second pulsed waveform, wherein the second pulsed waveform produces a second electric field having a second vector with a second controlled direction different than the first controlled direction toward the target tissue, the first electric field and the second electric field configured to cause irreversible electroporation of the target tissue,
- wherein the at least three electrodes remain substantially fixed in position relative to the target tissue during selective activation of the first subset and the second subset.
1 more element
A method for ablating a target tissue of a heart, comprising:
- selectively activating a first subset of at least three electrodes of an ablation system to produce a first pulsed waveform, wherein the first pulsed waveform produces a first electric field having a first vector with a first controlled direction toward the target tissue;
- and
- selectively activating a second subset of the at least three electrodes within a length of time equal to two cardiac cycles of a subject after selective activation of the first subset, the second subset different than the first subset, to produce a second pulsed waveform, wherein the second pulsed waveform produces a second electric field having a second vector with a second controlled direction different than the first controlled direction toward the target tissue, the first electric field and the second electric field configured to cause irreversible electroporation of the target tissue.
Dependencies are inferred from the claim text.