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US 2026/0166096 A1Published application
A multifunctional vulnerary composition
OwnerCarlos ALVARADOinventor
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OwnerCarlos ALVARADOinventor
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The present invention discloses a new multifunctional vulnerary composition, comprising a combination of natural ingredients that work synergistically in the reconstruction of skin tissues in mammals, affected by a variety of injuries or conditions, due to trauma, disease, or surgery. The natural ingredients herein, of bee honey, trigonelline (N-methylnicotinic acid), and zinc oxide, whose simultaneous antioxidant, antimicrobial, anti-inflammatory, and immunomodulatory properties, offer innovative strategies for restorative-regenerative skin injuries. Surprisingly, it has been discovered that by combining honey, trigonelline (N-methylnicotinic acid) and zinc oxide in precise proportions, provide a comprehensive, safe, and effective solution for the repair-regeneration and restructuring of the mammal's skin wounds. By taking advantage of the potential of this composition, health professionals optimize solve the problems of chronic wounds or tissues affected by injuries or conditions in a minimum of time and improve the quality of life of subjects who present these conditions.
1- A composition for promoting or expedite tissue repair, regeneration, and restructuring of damaged skin tissues in mammals, which is characterized by comprising:
2- The composition of claim 1, wherein the honey is present in a concentration range of 5-30% by weight, wherein the trigonelline extract is present in a concentration range of 3-15% by weight, wherein the zinc oxide is present in a concentration range of 2-20% by weight and wherein the excipients are present in a concentration range of 45-55% by weight.
3- The composition of claim 1, wherein the honey present in a concentration range preferably of 15-22% by weight, trigonelline extract present in a concentration range preferably of 2-8% by weight, zinc oxide present in a concentration range preferably of 10-17% by weight and excipients accounting for 54.4% by weight including a pH-modifying constituent in an amount sufficient to adjust the Ph to a value of 3.5-5.
4- The composition of claim 1, wherein the composition is formulated into topical preparations, including pastes, creams, lotions, serums, gels, hydrogels, hydrocolloids, and films.
5- A method of preparing a composition for promoting or expeditious tissue repair, regeneration, and restructuring of damaged skin tissues in mammals, which is characterized by the following steps:
6- A method for promoting or expedite tissue repair, regeneration, and restructuring of damaged skin tissues in mammal, said method comprising: