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US 2026/0166087 A1Published application
Compositions and methods for treating acute respiratory distress syndrome
AssigneeDirect Biologics, LLC
InventorTimothy Alexander Moseley
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Abstract
Compositions and methods for treating ARDS are provided, including compositions comprising one or more proteins and one or more extracellular vesicles.
Claims15
1-19. (canceled)
A composition comprising:
- a secretome of a cultured bone marrow-derived mesenchymal stem cell (MSC),
- wherein said secretome comprises:
- (a) one or more MSC-derived growth factors;
- and
- (b) MSC-derived extracellular vesicles;
- wherein said one or more MSC-derived growth factors comprise neuregulin1-B1 (NRG1-B1) or urokinase type plasminogen activator receptor (uPAR), and
- wherein said composition is a cell-free composition.
4 more elements
Dependencies are inferred from the claim text.