US 2026/0159805 A1 · LIMOSILACTOBACILLUS MUCOSAE AND DISORDERS REQUIRING A GLP-1 INCREASE

Limosilactobacillus mucosae and disorders requiring a glp-1 increase

AssigneesInstitut National De Recherche Pour L'agriculture, L'alimentation Et L'environnement, Institut National Des Sciences Et Industries Du Vivant Et De L'environnement, Universite Clermont Auvergne, Inst Ens Sup Rech Alimentation Sante Animale Sciences Agronomiques Et Environnement (Vetagro Sup), Assistance Publique-Hopitaux de Paris, Université Paris Cité, Universite Paris-Saclay

InventorsIsabelle SAVARY-AUZELOUX, Muriel THOMAS, Christophe CHASSARD, Muriel GIRON, Dominique DARDEVET, Marianne JARZAGUET, Camille MAYEUR, Françoise JOLY, Stéphanie BORNES

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Abstract

The present invention relates to a bacterial strain of the species Limosilactobacillus mucosae, or a lysate or culture supernatant thereof, for use in the prevention and/or treatment of disorders requiring an increase in GLP-1 production in a subject in need of GLP-1, the disorders being selected from (i) a disorder related to dysregulation of insulin sensitivity and/or blood glucose concentration and (ii) loss of muscle mass and/or muscle function.

Claims15

Dependent claims

A method for preventing or treating a disorder requiring an increase in production of GLP-1 in a subject in need thereof, comprising providing the subject with a bacterial strain of the species Limosilactobacillus mucosae, or a lysate or a culture supernatant thereof, wherein said disorders being selected from (i) a disorder linked to dysregulation of insulin sensitivity and/or blood sugar and (ii) loss of muscle mass and/or muscle function.

Dependencies are inferred from the claim text.

Facts

Application

19/129,197Filed 17 Nov 2023

Priority

FR FR221196417 Nov 2022

Published

11 Jun 2026

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Classification20 codes

C12N 1/205
Bacteria; Culture media therefor: bacterial isolates
A23L 33/135
Using additives: bacteria or derivatives thereof, e.g. probiotics
A61K 35/744
Probiotics: lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
A61K 36/064
Ascomycota: saccharomycetales, e.g. baker's yeast