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AssigneeZIVO Bioscience, Inc.
InventorsAmy E. Steffek, William P. Pfund, Andrew A. Dahl
Estimating the term…
A treatment compound and its use in the prevention and treatment diseases are disclosed. The compound comprises one or more materials selected from an algal biomass/supernatant (including both algae and bacteria), a bacterial biomass, and isolated and purified compound(s) as well as specific active sites or structures on those compounds. The treatment compound and the use of such a compound such as that derived from a bacterium that appears to selectively alter one or more TLR pathways in the prevention and treatment of disease in both animals and humans. The bacteria are selected from the group consisting of Algoriphagus sp., Bosea sp., Brevundimonas sp., Desulfovibrio sp., Microbacterium sp., Sphingomonas sp., and Variovorax sp. The disclosed inventive compound and method of treatment find particular application in the treatment of disease in poultry, particularly in the prevention and treatment of coccidiosis.
1-25. (canceled)
A composition for use in feed for the treatment of an enteric disease in poultry through modulation of at least one Toll-Like Receptor (TLR) pathway, the composition derived from the group consisting essentially of a biomass containing Gram-negative bacteria, a supernatant from an algal culture containing an algal organism and Gram-negative bacteria, a bacterial biomass containing Gram-negative bacteria, a lipopolysaccharide-Lipid A compound derived from a bacterial strain, a cellular component, fraction or extract derived from a bacterial strain containing lipopolysaccharide-Lipid A, and a lipopolysaccharide-Lipid A derivative from a bacterial strain, the composition including a bacterial biomass as a portion of finished feed, wherein the bacterial biomass includes three bacteria, Brevundimonas sp., Sphingomonas sp., and Microbacterium sp, and wherein the animals being treated are poultry.
A biomass-based composition for use in poultry feed derived from the group consisting essentially of a biomass containing Gram-negative bacteria, a supernatant from an algal culture containing an algal organism and Gram-negative bacteria, a bacterial biomass containing Gram-negative bacteria, a lipopolysaccharide-Lipid A compound derived from a bacterial strain, a cellular component, fraction or extract derived from a bacterial strain containing lipopolysaccharide-Lipid A, and a lipopolysaccharide-Lipid A derivative from a bacterial strain, more particularly the composition consisting essentially of three bacteria in the poultry feed in an amount from about 60.0 g per ton of finished feed to about 100.0 g per ton finished feed,
Dependencies are inferred from the claim text.