Oral products having tailored performance
AssigneeAltria Client Services LLC
InventorJason MACKO
Life of this patent
Estimating the term…
Abstract
A method of manufacturing an oral product includes preparing a wet granulation. The wet granulation includes a binder, a flavorant, and a solvent. The solvent is present in an amount ranging from 12 weight percent to 55 weight percent of the wet granulation. The method further includes forming a physical hydrogel by hydrogen bonding at least a portion of the flavorant to at least a portion of the binder. The forming includes removing at least a portion of the solvent. The method further includes incorporating the physical hydrogel into an oral product including an active ingredient.
Claims20
A method of manufacturing an oral product comprising:
- preparing a wet granulation including,
- a binder,
- a flavorant, and
- a solvent in an amount ranging from 12 weight percent to 55 weight percent of the wet granulation;
- forming a physical hydrogel by hydrogen bonding at least a portion of the flavorant to at least a portion of the binder, the forming including,
- removing at least a portion of the solvent;
- and
- incorporating the physical hydrogel into an oral product including an active ingredient.
A method of manufacturing a prolonged release oral product comprising:
- preparing a wet granulation including,
- a binder,
- a flavorant including,
- a hydrogen bonding donor site having a dipole moment magnitude of greater than or equal to about 2 D, and
- a hydrogen bonding acceptor site having a dipole moment magnitude of greater than or equal to about 2 D, and
- a solvent in an amount ranging from 12 weight percent to 55 weight percent of the wet granulation;
- forming a physical hydrogel by hydrogen bonding at least a portion of the flavorant to at least a portion of the binder, the forming including,
- removing at least a portion of the solvent;
- and
- incorporating the physical hydrogel into an oral product including an active ingredient.
A method of manufacturing a delayed release oral product comprising:
- preparing a wet granulation including,
- a binder,
- a flavorant including,
- one or more hydrogen bonding sites, all of the one or more hydrogen bonding sites being hydrogen bond donor sites or all of the one or more hydrogen bonding sites being hydrogen bond acceptor sites, and
- a solvent in an amount ranging from 12 weight percent to 55 weight percent of the wet granulation;
- forming a physical hydrogel by hydrogen bonding at least a portion of the flavorant to at least a portion of the binder, the forming including,
- removing at least a portion of the solvent;
- and
- incorporating the physical hydrogel into an oral product including an active ingredient.
Dependencies are inferred from the claim text.