A product of manufacture for inactivating a microbe, optionally a bacteria or a virus,
- wherein the product of manufacture is configured or manufactured to move air or force air under pressure, or create a positive air pressure flow of air, through a first duct, ductwork, vent, port, plenum (optionally an air delivery plenum and/or an air return plenum) and/or tube from an intake point, opening or value to an output point, opening or value,
- and the product of manufacture comprises:
- (a) a heating unit capable of or for heating the air (optionally forced air or positive air pressure flow of air) passing through the first duct, ductwork, vent, port, plenum and/or tube of the product of manufacture, wherein the heating unit is positioned at any point in the first duct, ductwork, vent, port, plenum and/or tube from the intake point, opening or value to the output point, opening or value,
- and the heating unit is capable of heating the air to a temperature of between about 175° C. to about 500° C., or between about 200° C. to about 450° C., or between about 250° C. to about 400° C., and
- a cooling unit operatively connected to the first duct, ductwork, vent, port, plenum and/or tube distal to the heating unit (between the heating unit and the output point, opening or value), and/or a cool or cold air intake duct, ductwork, vent, port, plenum, tube or value operatively connected to the first duct, ductwork, vent, port, plenum and/or tube distal to the heating unit, when cool or cold air is pumped or forced into the first duct, ductwork, vent, port, plenum and/or tube distal to the heating unit to lower the temperature of the air heated by the heating unit,
- wherein optionally the cooling unit and/or the cool air intake duct, ductwork, vent, port, plenum, tube or value is configured, set or adjusted to lower the temperature of the heated air to between about to between about 50° C. to about 175° C., or between about 40° C. to about 150° C.,
- and optionally the cooling unit comprises an air conditioning unit, optionally capable of delivering air having a temperature of between about 4° C. to about 40° C. to the first duct, ductwork, vent, port, plenum and/or tube distal to the heating unit
- (b) at least one or a plurality of air ionizers or ionizing devices capable of generating negative ionizations in an electric field in air (optionally forced air or positive air pressure flow of air) passing through the first duct, ductwork, vent, port, plenum and/or tube of the product of manufacture, wherein the at least one air ionizer or ionizing device is positioned at any point in the first duct, ductwork, vent, port, plenum and/or tube from the intake point, opening or value to the output point, opening or value,
- and a positively charged collector plate coupled with or operatively connected to each of the at least one or plurality of air ionizers or ionizing devices, wherein the positively charged collector plate is positioned distal (between the at least one air ionizer or ionizing device and the output point, opening or value) to each of the at least one or plurality of air ionizers or ionizing devices,
- and optionally the product of manufacture comprises two, three or four or more air ionizers or ionizing devices in the first duct, ductwork, vent, port, plenum and/or tube, or
- (c) a combination of the heating device of (a) and the air ionizer or ionizing device of (b), wherein optionally the at least one air ionizer or ionizing device is not positioned between the heating device and the cooling device.