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US 2026/0137828 A1Published application
Compositions and methods involving probiotic molecules
AssigneeMicroSintesis Inc.
InventorsMonica Angela Cella, Sarah M. Curtis, Jonathon Patrick Roepke
Life of this patent
Estimating the term…
Abstract
Provided are peptides that are derived from probiotic bacteria that may be useful for preventing and/or treating enteric infections or non-enteric infections in a subject. The peptides may also find use for reducing the virulence of enteric infections or non-enteric infections in a subject. Also provided are compositions of the peptides and compositions comprising culture fractions of the probiotic bacteria.
Claims20
A peptide comprising the amino acid sequence:
- a) MALPPK, wherein the peptide has fewer than 19 amino acid residues;
- b) CVLPPK, wherein the peptide comprises fewer than 68 amino acid residues;
- c) HLLPLP, wherein the peptide comprises fewer than 9 amino acid residues;
- d) XX[L or I]PPK, wherein each X independently designates a hydrophobic amino acid, wherein the peptide has fewer than 19 amino acid residues;
- e) X1X2[L or I]PPK, wherein X1 is selected from N, C, Q, M, S, and T and wherein X2 is selected from A, I, L, and V;
- or
- f) LPVPK, ALPK, EVLNCLALPK, LPLP, HLLPLPL, YVPEPF, KYVPEPF, or EMPFKPYPVEPF, wherein the peptide comprises 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, or 20 amino acid residues.
4 more elements
Dependencies are inferred from the claim text.