Oxazepine compounds comprising a 6-aza moiety and uses thereof

A compound or an atropisomer, stereoisomer, tautomer, or pharmaceutically acceptable salt thereof, having formula (I),

• wherein:
• Ring A is R8-substituted or unsubstituted 3-10 membered heterocycle, or R8-substituted or unsubstituted 5-10 membered heteroaryl;
• R8 is independently halogen, CN, NH2, NHC1-3alkyl, R8A-substituted or unsubstituted C1-6alkyl, or R8A-substituted or unsubstituted C1-6haloalkyl;
• R8A is halogen, unsubstituted C1-3alkyl, or unsubstituted C1-3haloalkyl;
• n is 1 or 2;
• R1 is R7-substituted or unsubstituted indolyl, R7-substituted or unsubstituted benzofuranyl, R7-substituted or unsubstituted naphthyl, R7-substituted or unsubstituted indazolyl, R7-substituted or unsubstituted indenyl, R7-substituted or unsubstituted benzothiazolyl, R7-substituted or unsubstituted isoquinolinyl, R7A-substituted or unsubstituted phenyl, or R7A-substituted or unsubstituted pyridinyl;
• each R7 is independently hydrogen, halogen, CN, CH2OH, —OH, NH2, N(Me)2, unsubstituted C1-3alkyl, unsubstituted C2-5 alkynyl, unsubstituted C1-3 haloalkyl, or unsubstituted cyclopropyl;
• each R7a is independently hydrogen, halogen, NH2, N(Me)2, unsubstituted C1-3 alkyl, unsubstituted C1-3haloalkyl, or unsubstituted cyclopropyl;
• R2 is OH, unsubstituted C1-3alkoxy, unsubstituted C1-3alkyl, or unsubstituted C1-3haloalkyl;
• R3 is R9-substituted or unsubstituted 4-10 membered heterocycle comprising N, S, or O;
• R9 is independently halogen, oxo, unsubstituted C1-3 alkyl, unsubstituted C1-3 haloalkyl, unsubstituted C1-3 alkoxy, R10-substituted or unsubstituted C1-3 alkylidene, or R10-substituted or unsubstituted C3-4 cycloalkyl, or R10-substituted or unsubstituted 3 or 4-membered heterocycle;
• or wherein two R9 together form a C3-5 cycloalkyl or 3-5 membered heterocycle;
• R10 is hydrogen or halogen;
• R4 is hydrogen, halogen, unsubstituted C1-3alkyl, unsubstituted C1-3alkoxy, or unsubstituted C1-3haloalkyl;
• and
• R5 and R6 are each independently hydrogen or unsubstituted C1-3alkyl.