Imaging slow flow dynamics of cerebrospinal fluid using magnetic resonance imaging
OwnerZijing Dong, Fuyixue Wang +3inventors
InventorsZijing Dong, Fuyixue Wang, Lawrence L. Wald, Laura Lewis, Jonathan Polimeni
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Abstract
Magnetic resonance imaging (MRI) is used to image the slow flow of cerebrospinal fluid (CSF) in subarachnoid and perivascular spaces, amongst other regions of the brain and central nervous system. The slow CSF flow imaging can be provided by using low velocity’ encoding (VENC) and an efficient data acquisition. Tailored image processing can be used to further improve the accuracy, specificity, and visualization of CSF flow dynamics.
Claims21
A method for cerebrospinal fluid (CSF) flow imaging with a magnetic resonance imaging (MRI) system, the method comprising:
- (a) acquiring magnetic resonance data from a subject with an MRI system, wherein the magnetic resonance data are acquired using a pulse sequence having velocity encoding gradients sufficient to encode slow flow of the CSF in the subject;
- (b) reconstructing phase contrast images from the magnetic resonance data using a computer system;
- (c) generating velocity images from the phase contrast images using the computer system, wherein the velocity images are indicative of the slow flow of the CSF in the subject;
- (d) generating CSF flow data from the velocity images using the computer system, wherein the CSF flow data are indicative of at least one of flow velocity magnitude, flow velocity direction, or flow volume of the CSF in the subject;
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- (e) outputting the CSF flow data using the computer system.
Dependencies are inferred from the claim text.