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US 2026/0130885 A1Published application
Antimicrobial compositions, pharmaceutical compositions and use thereof
AssigneesNational Taiwan University, National Yang Ming Chiao Tung University
InventorsHao-Chieh CHIU, Chung-Wai SHIAU
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Abstract
Disclosed herein are an antimicrobial composition and related methods. With the synergistic effect of amide compounds and fatty acids in the composition, not only the antibacterial effect against drug-resistant bacteria can be achieved with a smaller amount of amide compounds, but the persister cells and biofilms of microorganisms can be effectively and quickly eradicated.
Claims14
A method for inhibiting growth of a microbial cell and growth of a microbial biofilm with an antimicrobial composition, comprising:
- administering the antimicrobial composition to a mammal, wherein the antimicrobial composition comprises:
- an amide compound, wherein the amide compound is a malonamide derivative or a carbamide compound;
- and
- a fatty acid;
- wherein the fatty acid is a cis-unsaturated fatty acid with 16 to 22 carbon atoms.
2 more elements
Dependencies are inferred from the claim text.