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AssigneeMeso Scale Technologies, LLC.
InventorsJohn H. KENTEN, George SIGAL, Galina NIKOLENKO, Ryan CONNELLY
Estimating the term…
The disclosure relates to methods and kits for detecting, quantifying, or both, phosphorylated tau (p-tau) in a biological sample. The disclosure further provides methods for detecting brain-associated tau polypeptide, a brain injury or a neurodegenerative disease in a subject, determining the eligibility of individuals for participation in clinical trials for brain injury and/or neurodegenerative disease treatments, distinguishing between individuals with brain injury and/or neurodegenerative disease and without brain injury and/or neurodegenerative disease, and monitoring response to treatment of the same.
A method of detecting, quantifying, or both, phosphorylated tau (p-tau) in a biological sample, wherein the p-tau is phosphorylated at two or more sites, comprising:
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A kit for detecting phosphorylated tau (p-tau) in a biological sample, wherein the p-tau is phosphorylated at two or more sites, comprising, in one or more vials, containers, or compartments, three reagents:
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A method of detecting, quantifying, or both, tau in a biological sample, wherein the tau comprises a plurality of detectable epitopes, the method comprising:
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A kit for detecting, quantifying, or both, tau in a biological sample, where the tau comprises at least one detectable epitope comprising a first site, wherein the kit comprises:
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Dependencies are inferred from the claim text.