Process for continuous manufacture of biomolecules

A method of continuous manufacturing of biomolecules, comprising:

• feeding a reaction chamber with products from feed tanks, the products forming a reaction phase in the reaction chamber;
• storing an immiscible phase that is not miscible with the reaction phase in a scale tank in fluid communication with the reaction chamber;
• controlling with a monitoring and control unit an injection flow rate of the immiscible phase into the reaction chamber to maintain a certain filling level of the reaction chamber according to an amount of reaction phase to be injected into the reaction chamber to manufacture a certain amount of biomolecules, so that the lower the amount of reaction phase to be injected into the reaction chamber and the higher the amount of immiscible phase to be injected;
• and
• manufacturing the biomolecules from the reaction phase in the reaction chamber.