Intraluminal device and method of applying stress to baroreceptors in the gastro-intestinal tract

A method of stimulating baro receptors at the cardiac portion of the stomach, comprising:

• fixing an intraluminal device to the cardiac portion of the stomach with a magnetic fastener, said intraluminal device comprising a wall defining a baro receptor stimulating surface, said baro receptor stimulating surface and the cardiac portion of the stomach being conformable with each other, said method comprising:
• said magnetic fastener having a magnet assembly and an attractor assembly, said magnet assembly generating magnetic flux and said attractor assembly being attracted to the magnet assembly in response to the magnetic flux;
• deploying a first assembly comprising said magnet assembly or said attractor assembly against the inner surface or an outer surface of the stomach at the cardiac portion of the stomach;
• deploying a second assembly having a wall and the other of said one chosen from said magnet assembly and said attractor assembly to the portion of the inner surface the stomach;
• and
• wherein magnetic attraction between said magnet assembly and said attractor assembly applies stress with the baro receptor stimulating surface to stimulate baro receptors at the cardiac portion of the stomach;
• and
• adjusting level of stimulation of the baro-receptors.

A method of stimulating baro receptors at the cardiac portion of the stomach, comprising:

• fixing an intraluminal device to the cardiac portion of the stomach with a magnetic fastener, said intraluminal device comprising a wall defining a baro receptor stimulating surface, said baro receptor stimulating surface and the cardiac portion of the stomach being conformable with each other, said method comprising:
• said magnetic fastener having a magnet assembly and an attractor assembly, said magnet assembly generating magnetic flux and said attractor assembly being attracted to the magnet assembly in response to the magnetic flux;
• deploying a first assembly comprising said magnet assembly or said attractor assembly against the inner surface or an outer surface of the stomach at the cardiac portion of the stomach;
• deploying a second assembly having a wall and the other of said one chosen from said magnet assembly and said attractor assembly to the portion of the inner surface the stomach;
• and
• wherein magnetic attraction between said magnet assembly and said attractor assembly applies stress with the baro receptor stimulating surface to stimulate baro receptors at the cardiac portion of the stomach;
• adjusting level of stimulation of the baro-receptors with a controller.
• wherein said controller is adapted to adjust level of stimulation of the baro-receptors by controlling stress applied by the baro receptor stimulating surface to the cardiac portion of the stomach including adjusting amount of current to at least one electro-magnet.

An intraluminal device that is adapted to apply stress to the cardiac portion of the stomach, comprising:

• a magnetic fastener;
• a wall defining a baro receptor stimulating surface, said baro receptor stimulating surface and the cardiac portion of the stomach conformable with each other;
• said magnetic fastener having a magnet assembly and an attractor assembly, said magnet assembly generating magnetic flux and said attractor assembly being attracted to the magnet assembly in response to the magnetic flux;
• a first assembly comprising said magnet assembly or said attractor assembly, said first assembly configured to be fixed against the inner surface or an outer surface of the stomach at the cardiac portion of the stomach;
• a second assembly having said wall and the other of said one chosen from said magnet assembly and said attractor assembly, said second assembly adapted to be deployed to the stomach;
• wherein the magnetic attraction between said magnet assembly and said attractor assembly applies stress with baro receptor stimulating surface of the intraluminal device to stimulate the baro receptors at the cardiac portion of the stomach;
• and
• wherein said second assembly comprises a plurality second assemblies with different stimulation levels, wherein amount of stress applied with the baro receptor stimulating surface to the cardiac portion of the stomach is selectable by replacing said second assembly with another second assembly having variation of at least one selected from (i) magnetic attraction strength, (ii) baro receptor stimulation contact area, (iii) baro receptor stimulation contact force, (iv) stiffness of the wall, (v) variation of thickness and/or distribution of material in the wall, (vi) weave of a structure wire, and (vii) material of the structure wire.

An intraluminal device that is adapted to apply stress to the cardiac portion of the stomach, comprising:

• a magnetic fastener;
• a wall defining a baro receptor stimulating surface, said baro receptor stimulating surface and the cardiac portion of the stomach conformable with each other;
• said magnetic fastener having a magnet assembly and an attractor assembly, said magnet assembly generating magnetic flux and said attractor assembly being attracted to the magnet assembly in response to the magnetic flux, said magnet assembly comprising at least one electro-magnet;
• and
• a first assembly comprising said magnet assembly or said attractor assembly, said first assembly configured to be fixed against the inner surface or an outer surface of the stomach at the cardiac portion of the stomach;
• and
• a second assembly having said wall and the other of said one chosen from said magnet assembly and said attractor assembly, said second assembly adapted to be deployed to the stomach;
• wherein the magnetic attraction between said magnet assembly and said attractor assembly applies stress with baro receptor stimulating surface of the intraluminal device to stimulate the baro receptors at the cardiac portion of the stomach;
• and
• a controller adapted to adjust level of stimulation of the baro-receptors by controlling stress applied by the baro receptor stimulating surface to the cardiac portion of the stomach including adjusting amount of current to said at least one electro-magnet.