System and method for generating sequences for therapeutic proteins

A protein sequence generation system for new therapeutic protein drug development, the system comprising:

• equipment for synthesizing a protein;
• a memory configured to store one or more instructions;
• and
• at least one processor configured to execute the one or more instructions stored in the memory,
• wherein operations performed by the one or more instructions comprise:
• a step of obtaining reference protein sequence information;
• a step of generating noise-added protein sequence information by repeatedly adding noise to the reference protein sequence information;
• and
• a step of generating noise-removed output protein sequence information from the noise-added protein sequence information,
• wherein the steps of the generating comprise:
• a step of generating the noise-removed protein sequence information by removing noise from input protein sequence information according to one or more protein structure guidances specified by a user;
• and
• a step of repeatedly performing all or part of a step of generating the noise-added protein sequence information by adding noise to the noise-removed protein sequence information according to one or more protein sequence guidances specified by the user,
• wherein all or part of the steps of the generating are repeatedly performed,
• wherein the noise-removed output protein sequence information resulting from a final iteration of the generating steps is used with the equipment to synthesize a candidate protein, and
• wherein, in relation to the reference protein, the candidate protein exhibits improved properties corresponding to the protein structure guidances.