Sensor, kit, and method for biomarker detection in saliva

Abstract

It is provided a sensor for measuring a biomarker or metabolite level such as glucose level in a fluid sample such as saliva comprising a sensing element comprising a redox reporter attached to at least one aptamer that binds to the biomarker or metabolite, and a solid surface where the sensing element is attached thereto, wherein upon binding of the biomarker or metabolite onto to the aptamer, the redox reporter undergoes a binding-induced change in electron transfer. Measuring the biomarker or metabolite level in the saliva of a patient will allow health monitoring in the patient such as increased risk of gum disease or diabetes in the patient.

Dependencies are inferred from the claim text.