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US 2026/0098245 A1Published application
Differentiation Method
AssigneeKoninklijke Nederlandse Akademie van Wetenschappen
InventorsJohannes Carolus Clevers, Helmuth Gehart
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Abstract
The invention relates to differentiation methods for progenitor cells, e.g. mammalian epithelial stem cells, differentiation media for use in said methods, organoids and cells obtainable by said methods and uses, including therapeutic uses, thereof.
Claims14
-40. (canceled)
An in vitro differentiated liver organoid comprising differentiated liver epithelial cells, wherein relative mRNA expression level of CK7 is less than 0.08 relative to GAPDH expression.
Dependencies are inferred from the claim text.