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US 2026/0097207 A1Published application
Bioelectronic Localized Antimicrobial Stimulation Therapy (BLAST) through selective excitability
AssigneesThe University of Chicago, The Regents of the University of California
InventorsBozhi Tian, Saehyun Kim, Gürol M. Süel
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Abstract
The present disclosure relates to a method of electrically stimulating a resident bacteria on an epidermis of an animal for bioelectronic localized antimicrobial stimulation therapy (BLAST) through selective excitability and a wearable electroceutical device to aid in such methods.
Claims20
A method of electrically stimulating a resident bacteria on an epidermis of an animal, the method comprising:
- applying an acidic hydrogel to a region of the epidermis of the animal containing the resident bacteria;
- covering the region with a bioelectronic device;
- and
- administering an electrical stimulus through the bioelectronic device to the region, wherein the electrical stimulus exerts an antimicrobial effect on the resident bacteria.
1 more element
A wearable electroceutical device, comprising:
- a first layer, wherein the first layer is a wearable film dressing;
- and
- a second layer applied to an interfacing side of the wearable film dressing, the second layer comprising:
- a flexible polymer substrate, and
- an electrode array integrated onto the flexible polymer substrate, wherein:
- the second layer is configured to be applied to a mammalian epidermis via the first layer, and
- an acidic hydrogel interlayer is configured to be disposed between the second layer and the mammalian epidermis.
4 more elements
Dependencies are inferred from the claim text.