Neurocatheters, systems, and methods of use

-21. (canceled)

-88. (canceled)

An intravascular catheter comprising a catheter body having a proximal section, a distal section, and a transition section disposed between the proximal section and the distal section,

• wherein the proximal section of the catheter body comprises a proximal end region of a metallic hypotube comprising a first plurality of cuts forming a first plurality of tube segments, the proximal end region having a proximal bending stiffness along a proximal length that is greater than about 10 N,
• wherein the transition section of the catheter body comprises a distal end region of the metallic hypotube comprising a second plurality of cuts forming a second plurality of tube segments, the distal end region having a distal bending stiffness and a distal length, wherein the distal bending stiffness changes over the distal length by at least 10×, the distal length being less than about 30 cm, and
• wherein the distal section of the catheter body comprises a flexible polymer tube including a coil reinforcement disposed between an inner polymer layer and an outer polymer layer.

A neurocatheter comprising a catheter body defining an inner lumen having a working length between a proximal end and a distal end of the catheter body, wherein the catheter body comprises a proximal section, a transition section and a distal section, wherein the proximal section is stiffer than the distal section by at least 10×,

• wherein the catheter is capable of being advanced through a patient's vasculature to the neurovasculature without being positioned inside an outer catheter except for a short introducer sheath at the access location having a length less than about 30 cm, so the distal section reaches the middle cerebral artery without prolapse of the proximal section.