Hydrophobically-modified polymers with benzenediol functional groups and oxidized forms thereof

Abstract

The present disclosure provides hydrophobically-modified biopolymers, including hydrophobically-modified chitosans, which comprise benzenediol groups, optionally where a portion are oxidized to the corresponding quinone. The biopolymers demonstrate a surprising ability to tune mucoadhesive properties, material cohesive properties, and hemostatic action of the material, to provide next generation hemostats, among other uses. Accordingly, in other aspects, the disclosure provides compositions comprising the modified biopolymers of the disclosure as well as methods for bleed and wound treatment.

Dependencies are inferred from the claim text.