Back to results
US 2026/0097140 A1Published application
Radiolabelled Compounds
AssigneesThe University of Melbourne, Peter MacCallum Cancer Institute
InventorsAsif NOOR, Peter Douglas ROSELT, Paul Stephen DONNELLY
Life of this patent
Estimating the term…
Abstract
Processes for the synthesis of [89Zr]ZrCl4 from [89Zr][Zr(oxalate)4]4− salt are provided. The [89Zr]ZrCl4 can be reacted with biomarker targeting agents to produce 89Zr labelled radiopharmaceuticals. The 89Zr labelled radiopharmaceuticals find use in, for example, non-invasive molecular imaging.
Claims35
A process for the synthesis of [89Zr]ZrCl4 solution comprising:
- (a) contacting a solution comprising [89Zr][Zr(oxalate)4]4− salt with a porous solid having anion exchange capacity, said porous solid comprising ligands covalently attached thereto, said ligands comprising ion exchange groups having a positive charge;
- (b) treating the porous solid with an acidic solution comprising chloride ions;
- and
- (c) recovering a solution comprising [89Zr]ZrCl4 from the porous solid.
1 more element
Dependencies are inferred from the claim text.