Conjugates
AssigneesOrum Therapeutics Inc., Bristol-Myers Squibb Company
InventorsNathan FISHKIN, Peter U. PARK
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Abstract
The present disclosure provides conjugates comprising a binding moiety and an immunomodulatory imide compound, e.g., substituted isoindoline compound, wherein the immunomodulatory imide compound is conjugated to a binding moiety via an optional linker. Also provided are compositions comprising the conjugates. The conjugates and compositions are useful for treating a disease or condition, e.g., cancer, in a subject in need thereof.
Claims92
A conjugate comprising a binding moiety that specifically binds to a protein, and an immunomodulatory imide compound, wherein the binding moiety and the immunomodulatory imide compound are linked via an optional linker (L).
Dependencies are inferred from the claim text.