Administration of glutathione trisulfide to ameliorate peripheral neuropathy
AssigneesThe General Hospital Corporation, Kyowa Hakko Bio Co., Ltd.
InventorsFumito Ichinose, III, Mariko Ezaka, Etsuo Ohshima
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Abstract
Methods and devices for the administration of compositions comprising glutathione trisulfide (GSSSG), pantethine trisulfide (PTN-SSS), or lipoic acid trisulfide (LA-SSS) to treat peripheral neuropathy, e.g., chemotherapy-induced peripheral neuropathy (CIPN), e.g., by oral or nasal administration. The methods can be used, e.g., to reduce pain associated with CIPN, or reduce the risk of development of CIPN.
Claims8
A method for the treatment, or reduction of risk, of a disorder associated with peripheral neuropathy in a subject, the method comprising administering a therapeutically or prophylactically effective amount of a composition comprising glutathione trisulfide (GSSSG), pantethine trisulfide (PTN-SSS), or lipoic acid trisulfide (LA-SSS) to a subject in need thereof, optionally comprising administering the GSSSG orally or nasally.
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Dependencies are inferred from the claim text.