Chimeric antigen receptors specific to b-cell mature antigen (bcma) and/or transmembrane activator and caml interactor (taci)

Abstract

Genetically engineered immune cells (e.g., T cells or NK cells) expressing anti-BCMA, anti-TACI, or anti-BCMA/anti-TACI chimeric antigen receptors and uses thereof in cancer therapy. In some embodiments, the genetically engineered immune cells may be armored CAR-T or CAR-NK cells, which further express an armor polypeptide for enhancing CAR-T or CAR-NK cell features.

Dependencies are inferred from the claim text.