Fluoro beta-carboline compounds
AssigneeOssifi Therapeutics LLC
InventorsDebra ELLIES, F. Scott KIMBALL, Robert N. YOUNG
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Abstract
In one aspect, the invention provides compounds of Formula I, and salts, hydrates and isomers thereof. In another aspect, the invention provides a method of promoting bone formation in a subject in need thereof by administering to the subject a therapeutically effective amount of a compound of Formula I. The present invention also provides orthopedic and periodontal devices, as well as methods for the treatment of renal disease, diabetes, bone loss, and cancer, using a compound of Formula I.
Claims22
1-52. (canceled)
A medical device comprising a structural support, wherein an implantable portion of the structural support is adapted to be permanently implanted within a subject, wherein the implantable portion is attached to a bone, the structural support bearing at least a partial external coating comprising a compound and/or the structural support comprising a compound within the support,
- wherein the compound is selected from the group consisting of:
- or a pharmaceutically acceptable salt, hydrate or prodrug thereof.
(canceled)
Dependencies are inferred from the claim text.