Liquid Formulation of Belumosudil
AssigneeKadmon Corporation, LLC
InventorsOlivier Schueller, Galit Regev, Mark Beville, Nazim Kanji
Life of this patent
Estimating the term…
Abstract
The present disclosure provides liquid formulations comprising belumosudil, processes for preparing a liquid formulation of belumosudil, and liquid pharmaceutical compositions comprising belumosudil which may be used in the treatment of subjects.
Claims41
A liquid formulation comprising 2-{3-[4-(1H-indazol-5-ylamino)-2-quinazolinyl]phenoxy}-N-(propan-2-yl)acetamide or a pharmaceutically acceptable salt thereof (belumosudil) in a diluent in combination with a suspending agent, a thickener, and an antifoaming agent.
A liquid formulation comprising 2-{3-[4-(1H-indazol-5-ylamino)-2-quinazolinyl]phenoxy}-N-(propan-2-yl)acetamide or a pharmaceutically acceptable salt thereof (belumosudil) in a diluent in combination with a suspending agent and a thickener.
A process for preparing a liquid formulation comprising belumosudil comprising mixing jet-milled and/or pin-milled belumosudil in a diluent with a suspending agent and a thickener.
A kit for preparing a liquid formulation of belumosudil comprising (a) in a first container, an amount of belumosudil;
- and (b) in a second container, a reconstitution vehicle comprising a suspending agent and a thickener in a diluent.
Dependencies are inferred from the claim text.