Pharmaceutical composition, and preparation method therefor and use thereof
OwnerYuanyuan XIE, Lina QI +3inventors
InventorsYuanyuan XIE, Lina QI, Can HUANG, Jiong LAN, Qiang LU
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OwnerYuanyuan XIE, Lina QI +3inventors
InventorsYuanyuan XIE, Lina QI, Can HUANG, Jiong LAN, Qiang LU
Estimating the term…
A pharmaceutical composition, and a preparation method therefor and the use thereof. The pharmaceutical composition contains: (4aR,8R)-3-acryloyl-11-chloro-10-(2-fluoro-6-hydroxyphenyl)-8-(2-isopropyl-4-methylpyridin-3-yl)-6-methyl-2,3,4,4a,6,8-hexahydro-1H-pyrazino[1′,2′:4,5]pyrazino[2,3-c][1,8]naphthyridin-5,7-dione or a pharmaceutically acceptable salt thereof as an active ingredient; and one or more selected from a filler, a disintegrant, a lubricant, a glidant and a binder. The pharmaceutical composition has good stability and drug dissolution, and the preparation process is simple and is suitable for industrial production.
A pharmaceutical composition, comprising (4aR,8R)-3-acryloyl-11-chloro-10-(2-fluoro-6-hydroxyphenyl)-8-(2-isopropyl-4-methylpyridin-3-yl)-6-methyl-2,3,4,4a,6,8-hexahydro-1H-pyrazino[1′,2′:4,5]pyrazino[2,3-c][1,8]naphthyridin-5,7-dione or a pharmaceutically acceptable salt thereof as an active ingredient, and one or more selected from a filler, a disintegrant, a lubricant, a glidant, and a binder.
(canceled)
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