Solid forms and salts of a quinoline cgas antagonist compound
AssigneesImmuneSensor Therapeutics, Inc., Board of Regents, The University of Texas System
InventorsJian Qiu, Qi Wei, Heping Shi, Lijun Sun, Zhijian Chen
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Abstract
The present disclosure provides compounds that are cGAS antagonists, solid forms of the compounds, methods of preparation of the compounds and their solid forms, pharmaceutical compositions comprising the compounds and their solid forms, and their use in medical therapy.
Claims48
A compound, wherein the compound is a solid form of Compound A:
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A compound, wherein the compound is a pharmaceutically acceptable salt of Compound A:
- wherein the pharmaceutically acceptable salt is selected from a hydrochloride, sulfate, napadisylate, esylate, mesylate, napsylate, besylate, sodium, potassium, L-arginine, choline, L-lysine, t-butylamine, meglumine, and tris(hydroxymethyl)aminomethane salt.
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Dependencies are inferred from the claim text.