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US 2026/0091092 A1Published application
Methods Of Treating Plantar Fibromatosis
AssigneeENDO Biologics, Inc.
InventorsJames P. Tursi, Luis A. Ortega, Qinfang Xiang, Saji Vijayan, Jeffrey David Lehrman, David Hernandez
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Abstract
Disclosed herein are methods of treating plantar fibromatosis in a subject or a population of subjects.
Claims29
A method of treating moderate to severe plantar fibromatosis in a subject or a population of subjects, the method comprising:
- intralesionally injecting a pharmaceutical formulation comprising collagenase into one or more plantar fibromatosis nodules in one or both of the subject's feet or the population of subjects' feet to thereby treat the plantar fibromatosis, wherein the dose of collagenase administered per nodule comprises about 0.45 mg to about 1.35 mg and the treating comprises:
- an improvement from baseline in nodule consistency;
- a reduction from baseline in the nodular hardness;
- or a combination thereof.
1 more element
A method of treating moderate to severe plantar fibromatosis in a subject or a population of subjects, the method comprising:
- intralesionally injecting a pharmaceutical formulation comprising collagenase into one or more plantar fibromatosis nodules in one or both of the subject's feet or the population of subjects' feet to thereby treat the plantar fibromatosis, wherein the dose of collagenase administered per nodule comprises about 0.6 mg, and the treating comprises:
- an improvement from baseline in nodule consistency;
- a reduction from baseline in the nodular hardness;
- or a combination thereof.
1 more element
Dependencies are inferred from the claim text.