Microrna and uses thereof in prevention and/or treatment of fibroplasia medical sign and/or syndrome

A polynucleotide comprising:

• A) a sequence set forth in any one of SEQ ID NO:
• 1, 2, 3, 4, 5, 6, 7, 9, 10, 12, 13, 14, 15, 16 and 17, or a complementary sequence thereof;
• B) a sequence having at least 80%, 85%, 90%, 95%, 96%, 97% or 98% identity to the sequence set forth in A), and capable of preventing/treating fibrosis;
• C) a sequence hybridizing to the sequence set forth in A) under a stringent condition, and capable of preventing/treating fibrosis;
• D) a sequence obtained by adding, deleting, or substituting one or more nucleotides in the sequence set forth in A), and capable of preventing/treating fibrosis;
• or
• E) a precursor or modified variant of the sequence set forth in A), B), C) or D), and capable of preventing/treating fibrosis.