Pharmaceutical topical formulations of lidocaine and ketamine

Abstract

The present invention provides a topical formulation comprising active ingredient(s) lidocaine, ketamine, or pharmaceutically acceptable salt thereof for dermal application and method of use to treat or relieve pain. The topical formulation comprises active pharmaceutical agents lidocaine, ketamine, or their pharmaceutical salt thereof; one or more skin penetration enhancers; and a drug delivery matrix system. The topical formulations are aimed at relieving pain including any type of pain in body, joint pain, chronic pain states such as post-herpetic neuralgia, complex regional pain syndrome, and arthritis. The topical formulation dries and forms a clear film on the skin and as it comprises water insoluble excipients, it is reasonably wash resistant.

Dependencies are inferred from the claim text.