Liver tumor detection in ct scans

A computer-implemented method of processing CT scan images comprising a liver of a subject to detect and/or predict hepatocellular carcinoma (HCC) in the subject, the method comprising the steps of:

• a. receiving at least two CT scan images comprising the liver, optionally comprising receiving annotations associated with the received CT scan images;
• and
• b. processing the received CT scan images, wherein processing comprises:
• i. selecting, from the received CT scan images, a reference CT scan image;
• ii. obtaining a reference liver mask for the selected reference CT scan image;
• iii. cropping, using the obtained reference liver mask, the selected reference CT scan image;
• iv. coregistering the remaining at least one CT scan image with the cropped reference CT scan image;
• v. optionally filtering the reference CT scan image and the coregistered at least one CT scan image.