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US 2026/0085352 A1Published application
Pulsed recharging for nanopore devices
AssigneeIllumina, Inc.
InventorsChristian Urban, Birch Simpson
Life of this patent
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Abstract
Systems and methods for nanopore sequencing are disclosed. The systems and methods are related to using pulsed voltage waveforms to replenish depleted ions in nanopore unit cells.
Claims20
A method of sequencing nucleic acids using an array of nanopore cells, each nanopore cell comprising a protein nanopore, a trans well and a trans electrode, the method comprising controlling at least one nanopore cell by:
- (a) applying a sequencing waveform across the protein nanopore of the at least one nanopore cell, resulting in depletion of electrolytes in the trans well of the at least one nanopore cell;
- and
- (b) applying a pulsed recharging waveform across the protein nanopore, resulting in replenishment of electrolytes in the trans well.
Dependencies are inferred from the claim text.