US 2026/0085318 A1Published application

Methods for Treating Cancer Using a Stat3 Double-Stranded, Cyclic Oligonucleotide Decoy

OwnerDaniel E. Johnson, Jennifer R. Grandisinventors

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Abstract

The present invention provides methods of treating cancer using a STAT3 double-stranded, cyclic oligonucleotide decoy in combination with an immune checkpoint inhibitor.

Claims28

Dependent claims

A method of treating cancer in a patient, comprising administering to a patient in need thereof a therapeutically effective amount of a STAT3 double-stranded, cyclic oligonucleotide decoy and an immune checkpoint inhibitor, to treat the cancer.

Dependencies are inferred from the claim text.

Facts

Application: 19/112,832Filed 20 Sep 2023
Priority: 23 Sep 2022
Published: 26 Mar 2026
Term ends: Not estimatedThe source records don’t support an estimate.

Classification16 codes

A61K 45/06
Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00: mixtures of active ingredients without…
C12N 15/1136
Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming…: against…
A61K 31/711
Compounds having three or more nucleosides or nucleotides: natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to…
A61K 31/713
Compounds having three or more nucleosides or nucleotides: double-stranded nucleic acids or oligonucleotides

Family

Application63/409,520Us provisional application · filed 23 Sep 2022
US 2026/0085318 A1This patent

From the US filing history. Foreign family members aren’t listed.

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