Systems and compositions for fusion polypeptides and methods of use thereof

Abstract

The present disclosure provides polypeptide molecules comprising one or more polypeptide chains and systems, compositions, and methods of use thereof, wherein the polypeptide molecule comprising one or more polypeptide chains (or engineered polypeptide chain) can be used to effect regulation of a target gene in a cell (e.g., an endogenous target gene in a cell).

Dependencies are inferred from the claim text.