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US 2026/0085071 A1Published application
Novel crystalline form of 1-(8-bromopyrido[2,3- e][1,2,4]triazolo[4,3-a]pyrazin-4-yl)-nmethylazetidin- 3-amine
AssigneeJw Pharmaceutical Corporation
InventorsSuha PARK, Seiho CHIN, Sumin LEE
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Abstract
Novel crystalline forms of 1-(8-bromopyrido[2,3-e][1,2,4]triazolo[4,3-a]pyrazin-4-yl)-N-methylazetidin-3-amine is provided along with pharmaceutical compositions comprising the same. Also disclosed is the use of the novel polymorph for the treatment of diseases, such as atopic dermatitis (AD), itch, pruritus and various forms of urticaria for example chronic idiopathic urticaria subtypes.
Claims16
Crystalline 1-(8-bromopyrido[2,3-e][1,2,4]triazolo[4,3-a]pyrazin-4-yl)-N-methylazetidin-3-amine form A characterized by one or more XRPD reflections at approximately (°2θ) 7.0, 22.6 and/or 26.3 (±0.2 degrees).
Dependencies are inferred from the claim text.