Automated Optimization of Deep Brain Stimulation (DBS) Parameters Using Weighted Targets and Avoidance Regions
AssigneeBoston Scientific Neuromodulation Corporation
InventorsMahsa Malekmohammadi, Richard Mustakos, Stephen Carcieri, Peter Yoo
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Abstract
Methods and systems for assisting the programming of stimulation parameters for deep brain stimulation (DBS) for a patient are described. Target regions for stimulation and avoidance regions where stimulation is to be avoided can be identified and weights can be associated with the target and avoidance regions. The described methods and systems use the weights to optimize stimulation.
Claims20
A method executed on an external programmer for programming a pulse generator (PG) for providing deep brain stimulation (DBS) to a patient having one or more electrode leads implanted in the patient's brain, wherein each electrode lead comprises a plurality of electrodes, the method comprising:
- receiving from a user interface (UI) of the external programmer an indication of at least one target region in the patient's brain to be stimulated,
- receiving from the UI an indication of two or more avoidance regions in the patient's brain for which stimulation is to be preferentially avoided,
- receiving from the UI an indication of weights assigned to each of the two or more avoidance regions, wherein at least two of the weights are different,
- for each of a plurality of trial stimulation parameter sets, using control circuitry of the external programmer to:
- determine a volume of the at least one target region that will be stimulated by electrical stimulation using the trial parameter set,
- determine a volume of each of the avoidance regions that will be stimulated by electrical stimulation using the trial parameter set,
- determine a metric based the volumes and the weights,
- using the control circuitry to use the metrics to select a therapeutic stimulation parameter set from the plurality of trial stimulation parameter sets, and
- using the control circuitry to program the PG with the therapeutic stimulation parameter set.
The method of 18, further comprising using the UI to display a representation of the one or more electrode leads overlaid with the images representative of the one or more target regions and the at least two avoidance regions.
Dependencies are inferred from the claim text.