System and method for individualized plasma donation

A system for collecting plasma comprising:

• a venipuncture needle configured to draw whole blood from a donor;
• a blood separator configured to separate the whole blood into a plasma product and a second blood component comprising red blood cells, the blood separator having a plasma output port coupled to a plasma line configured to send the plasma product to a plasma product collection container;
• a donor line fluidly coupled to the venipuncture needle configured to introduce the whole blood from the donor to the blood separator, flow through the donor line being controlled by a first pump;
• an anticoagulant line coupled to an anticoagulant source, the anticoagulant line configured to combine anticoagulant with the whole blood from the donor, flow through the anticoagulant line being controlled by a second pump;
• a user interface configured to receive input from an operator;
• and
• a controller coupled to the user interface and configured to receive donor information and demographic information, the controller programmed to (1) determine a target volume of plasma to collect based, at least in part, on the received donor information, (2) determine a plasma collection protocol based, at least in part, on the received donor information, the plasma collection protocol having a plurality of collection parameters and a plurality of process parameters, (3) adjust at least one of the plurality of collection parameters and/or the plurality of process parameters based on the donor information and/or the demographic information, and (4) control a plasma collection procedure according to the determined plasma collection protocol and adjusted collection parameters and/or process parameters, the plasma collection procedure having a plurality of draw cycles and a plurality of return cycles.