Methods and reagents for tumor targeting with greater efficacy and less toxicity
AssigneeCornell University
InventorNeil H. BANDER
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Abstract
The present invention relates to a method for treating cancer. This method involves providing a first agent comprising a first targeting component coupled to a first cancer therapeutic component and providing a second agent comprising a second targeting component coupled to a second cancer therapeutic component. The first and second targeting components have different biodistributions and/or pharmacokinetics. The first and second agents are administered to a subject having cancer to treat the cancer. Also disclosed is a combination therapeutic comprising the first and second agents.
Claims47
A method of treating cancer, said method comprising:
- providing a first agent comprising a first targeting component coupled to a first cancer therapeutic component;
- providing a second agent comprising a second targeting component coupled to a second cancer therapeutic component, wherein the first and second targeting components have different biodistributions and/or pharmacokinetics in the subject;
- and
- administering, to a subject having cancer, the first and second agents to treat cancer.
A combination therapeutic for treating cancer comprising:
- a first agent comprising a first targeting component coupled to a first cancer therapeutic component and
- a second agent comprising a second targeting component coupled to a second cancer therapeutic component, wherein the first and second targeting components have different biodistributions and/or pharmacokinetics.
Dependencies are inferred from the claim text.