Operator-independent histotripsy device
OwnerAmeer E. Hassan, Yousef Hasan Ahmad Khaliliinventors
Life of this patent
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Abstract
A histotripsy device includes a first arm, a second arm spaced apart from the first arm, and a first probe unit. The first probe unit is mounted to the first arm and positioned such that, with the first and second arms coupled to the cranium, the first probe unit is positioned over and in contact with one of a left and right temporal region of the cranium. The first probe unit has a first transducer array configured to emit focused radiation at an ultrasonic frequency or frequency range and a first transcranial doppler probe moveable relative to the first transducer array and configured to emit sound waves.
Claims20
A histotripsy device, comprising:
- a first arm and a second arm spaced apart from the first arm, the first and second arms configured to be coupled to a cranium of a human or animal to locate the cranium between the first arm and the second arm,
- a first probe unit mounted to the first arm and positioned such that, with the first and second arms coupled to the cranium, the first probe unit is positioned over and in contact with one of a left and right temporal region of the cranium, the first probe unit having a first transducer array configured to emit focused radiation at an ultrasonic frequency or frequency range and a first transcranial doppler probe moveable relative to the first transducer array and configured to emit sound waves,
- at least one processor, and
- at least one memory having instructions stored therein executable by the at least one processor to cause the at least one processor to activate the first transcranial doppler probe to produce the sound waves to determine a location of a blood clot and, in response to determining the location of the blood clot, to activate the first transducer array to produce at least one pulse of ultrasonic radiation to treat the blood clot.
A histotripsy device, comprising:
- a first arm configured to be coupled to a cranium of a human or animal,
- a first probe unit mounted to the first arm and positioned such that, with the first arm coupled to the cranium, the first probe unit is positioned over and in contact with one of a left and right temporal region of the cranium, the first probe unit having a first transducer array configured to emit focused radiation at an ultrasonic frequency or frequency range and a first transcranial doppler probe configured to emit sound waves, the first transducer array including seven annular segments that each extend around a central axis,
- at least one processor, and
- at least one memory having instructions stored therein executable by the at least one processor to cause the at least one processor to activate the first transcranial doppler probe to produce the sound waves to determine a location of a blood clot and, in response to determining the location of the blood clot, to activate the first transducer array to direct at least one pulse of ultrasonic radiation into the blood clot.
A method comprising:
- positioning a cranium of a human or animal between a first arm and a second arm of a histotripsy device,
- activating a first transcranial doppler probe coupled to the first arm to detect a location of a blood clot, and
- based on the location of the blood clot, and without moving the cranium, activating a first transducer array coupled to the first arm to direct at least one pulse of ultrasonic radiation toward the blood clot.
Dependencies are inferred from the claim text.