Embolic compositions containing dissipatable additive

Abstract

Embolic compositions include a carrier liquid that solidifies to form a solid occlusion matrix at a target site in a blood vessel, and a dissipatable solid additive contained within the carrier liquid. The dissipatable solid additive includes microparticles that are substantially insoluble in the carrier liquid, that are dispersed in the matrix upon solidification of the matrix, and that are dissipated out of the matrix by action of blood flow in the blood vessel against the matrix. Thereby, the matrix develops a porous structure and the blood vessel at the target site is less than totally occluded after dissipation of the additive. Methods of occluding a blood vessel include injecting the embolic composition to a target site in a blood vessel, allowing the embolic composition to solidify, and allowing the dissipatable solid additive to be dissipated from the solid occlusion matrix by blood flow in the blood vessel.

Dependencies are inferred from the claim text.