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US 2026/0077202 A1Published application
Systems and methods for administering and assessing brain stimulation
AssigneeDuke University
InventorsWarren Grill, Kay Palopoli
Life of this patent
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Abstract
Embodiments of present disclosure provide systems and methods relating to neuromodulation. In particular, the present disclosure provides systems and methods for administering deep brain stimulation (DBS), and for evaluating the efficacy and efficiency of DBS for the treatment of neurological conditions (e.g., Parkinson's disease).
Claims28
A method of administering brain stimulation therapy to a subject, the method comprising:
- delivering a temporally non-regular pattern of electrical stimulation to the subject's brain;
- measuring at least one neural biomarker in the local field potential (LFP);
- and
- treating at least one symptom in the subject.
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A system for administering brain stimulation therapy to a subject, the system comprising:
- at least one implantable electrode configured to deliver electrical stimulation and to record electrical signals in the subject's brain;
- and
- a pulse generator electronically coupled to the at last one implantable electrode, wherein the pulse generator is configured to deliver a temporally non-regular pattern of electrical stimulation and measure at least one neural biomarker in the local field potential (LFP).
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Dependencies are inferred from the claim text.